I have written this book to record my vision of the future of medicine based on observations made during my 55 years of basic and clinical research, teaching and medical practice. The book presents my views on the current crisis in healthcare and the ramifications of the Affordable Care Act, colloquially referred to as Obamacare, for the future of the healthcare industry, especially, in the United States. I have tried to touch on just about every aspect of medical practice especially as I see changes coming as a result of the Affordable Care Act and financial stresses. The discussions are terse but they are frank and present realities of the dilemmas facing the healthcare industry in the United States. This book was not written just for physicians and persons involved with the healthcare industry. Lay persons in the United States are very concerned with the future of healthcare and this book may help them to appreciate the stresses faced by physicians and hospitals in caring for patients. Moreover, the Affordable Care Act will be the subject of repeated discussions in the Congress, in newscasts and in newspapers. I hope that this book will add insight to these discussions.